Cardiac troponin I level in healthy newborn babies in Ilorin, North‑Central Nigeria

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Published: Jul 1, 2022
DOI: https://doi.org/10.60787/jmwan-v6i1-9
Keywords:
term, Nigeria, newborn babies, healthy, Cardiac troponin I

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Amudalat Issa
Department of  paediatrics, Children  Specialist Hospital,  Ilorin
Mohammed Baba Abdulkadir
Department of  Paediatrics and Child  Health, University of  Ilorin Teaching Hospita
Olayinka R. Ibrahim
Department of  Paediatrics and Child  Health, University of  Ilorin Teaching Hospital
Habibat Suberu
Department of  Paediatrics and Child  Health, University of  Ilorin Teaching Hospital
Ruqayat Ronke Bakare
Department of  Paediatrics and Child  Health, University of  Ilorin Teaching Hospital
Ibraheem Sanusi
Department of  Paediatrics and Child  Health, University of  Ilorin Teaching Hospital
Omotayo Olukemi Adesiyun
Department of  Paediatrics and Child  Health, University of Ilorin Teaching Hospital

Abstract

BACKGROUND: Cardiac troponins are reliable markers for the diagnosis of myocardial ischaemia. Cardiac troponin I is a valuable biomarker that has gained popularity across all ages including newborns. However, its usage in our environment in the paediatrics age group is limited probably because few studies have evaluated the normal levels in the healthy children. Hence, we determined the cardiac troponin I level in healthy term newborns.


METHODOLOGY: This was a cross‑sectional analytical study that involved 85 healthy term appropriate for gestational age newborns aged 24–72 h of life. The babies had relevant demographic parameters collected in a study pro forma. We determined the cardiac troponin I assay using enzyme‑linked immunosorbent assay (Enzyme linked immunosorbent assay method (ELISA)) method.


RESULTS: The median (interquartile range [IQR]) cardiac troponin I level was 0.79 (0.79–1.42) ng/ml. The cardiac troponin I level in male newborns, 1.05 (0.79–1.55) ng/ml, was higher but comparable with female newborns, 0.79 (0.79–1.00) ng/ml, P = 0.227. The cardiac troponin I increases with gestational age, P = 0.049. There was no relationship between cardiac troponin I level and birth weight, chronological age and mode of delivery (P > 0.05 in each).


CONCLUSION: The study demonstrated cardiac troponin I levels in healthy term Nigerian newborns with a significant relationship with gestational age.

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Issa, A., Abdulkadir, M. B., Ibrahim, O. R., Suberu, H., Bakare, R. R., Sanusi, I., & Adesiyun, O. O. (2022). Cardiac troponin I level in healthy newborn babies in Ilorin, North‑Central Nigeria. Journal of The Medical Women’s Association of Nigeria, 6(1), 17-20. https://doi.org/10.60787/jmwan-v6i1-9
Issue
Vol. 6 No. 1 (2021): July
Section
Original Article
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Author Biographies

Mohammed Baba Abdulkadir, Department of  Paediatrics and Child  Health, University of  Ilorin Teaching Hospita

Department of Paediatrics and Child Health, University of Ilorin, Ilorin, Kwara State, Nigeria

Omotayo Olukemi Adesiyun, Department of  Paediatrics and Child  Health, University of Ilorin Teaching Hospital

Department of Paediatrics and Child Health, University of Ilorin, Ilorin, Kwara State, Nigeria i

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