Complete Resolution Of A Huge Neck Mass (Non Hodgkins Lymphoma) Following Chemotherapy/Radiotherapy In A Nigerian Female - A Case Report.

Abstract

Introduction
Lymphomas are a group of cancers that affect the lymphatic system. There are two major types; Non-Hodgkin's lymphoma (NHL) which constitutes about 90% of cases and Hodgkin's lymphoma (HL) which constitutes about 10%. Lymphomas are gencrally chemo and radiosensitive.

Background
The patient presented, is a 45year old lady who had a 3-year history of neck swelling with histological diagnosis of a non-Hodgkin's lymphoma high grade type, stage III. She had six courses of chemotherapy CHOP(cyclophosphamide, doxorubicin, vincristine, and
prednisone) regimen by the haematologist for which she initially responded to.
Six months later she re-presented with local tumour recurrence, progressive increase in tumour size with severe bleeding which necessitated a referral to the radiation oncologists.
She subsequently had further chemotherapy and palliative radiotherapy and this resulted in a complete resolution of the tumour.

Conclusion

There was a complete tumour resolution despite the advanced stage and tumour size to chemoradiation therapy.